HansaBioMed Hollow Fiber Module, Polysulfone, TFF-MV

TFF-MV is a filter cartridge in hollow fibers made of polysulfone for separating different EVs by size. Indeed, microvesicles bigger than 150 nm are retained inside the hollow fibers, while small EVs and molecules easily permeate the filter. Microvesicles can be recovered with a syringe in PBS buffer, without additional purification steps.

The filter works with diluted matrices (cell media and urines) and with complex biofluids (plasma, serum etc.).

TFF-MV can be easily washed and it is reusable multiple times.

Advantages: Washable, reusable multiple times, easy to use.

Sample type	Diluted EV containing matrices (i.e. urine, conditioned cell media)
Quantity	1 concentrator
Filter cartridge	Polysulfone hollow fibres
Sample volume per reaction	Recommended sample volume from 10 ml up to several liters if connected to mechanical pump.
EV recovery	83%
Concentration time	From 5 minutes
Reusable	Up to 20 times
Applications	Separation of EVs by size. Recovering of big microvesicles in one step, without additional purification.